Foundayo® (Orforglipron) Weight Management Tablets
Foundayo contains orforglipron, a GLP-1 receptor agonist licensed in the UK for weight management in eligible adults when used alongside a reduced-calorie diet and increased physical activity.
Foundayo is supplied as a film-coated tablet taken once daily. It can be taken at any time of day, with or without food, and without specific water or fasting restrictions.
At a glance
- Active ingredient: Orforglipron
- Format: Film-coated tablet
- How often: Once daily
- Available strengths: 0.8 mg, 2.5 mg, 5.5 mg, 9 mg, 14.5 mg and 17.2 mg
- Prescription required: Yes
- Clinical assessment: Required before treatment can be supplied
How does Foundayo work?
Orforglipron acts on GLP-1 receptors in the body. GLP-1 is a naturally occurring hormone involved in appetite regulation, food intake and blood glucose control.
When prescribed for weight management, Foundayo is used alongside dietary changes and increased physical activity to support weight loss and long-term weight management.
Who may be eligible?
For weight management, Foundayo is licensed for adults with an initial BMI of 30 kg/m² or above, or a BMI of 27 kg/m² to below 30 kg/m² where at least one weight-related condition is also present. Examples include prediabetes or type 2 diabetes, high blood pressure, dyslipidaemia, obstructive sleep apnoea or cardiovascular disease.
Your medical history, current medicines, BMI and treatment goals must be reviewed by a prescriber before any prescription-only treatment is supplied.
Always take Foundayo exactly as prescribed by your clinician.
- Take one tablet once daily.
- It can be taken at any time of day.
- It can be taken with or without food.
- Swallow the tablet whole.
- Do not break, crush or chew the tablet.
- Do not take more than one tablet in a day.
Treatment normally begins with 0.8 mg once daily for 30 days. Your clinician may then gradually increase your dose depending on your response and tolerance.
If you forget a dose, take it as soon as you remember. Do not take more than one dose in the same day.
Do not change your dose or stop treatment without speaking to your clinician.
Active ingredient: Orforglipron.
Foundayo is available in the following strengths:
- 0.8 mg
- 2.5 mg
- 5.5 mg
- 9 mg
- 14.5 mg
- 17.2 mg
Other ingredients include: microcrystalline cellulose, crospovidone, copovidone, sodium carbonate anhydrous and magnesium stearate.
The tablet coating contains polyvinyl alcohol, titanium dioxide, macrogol, talc and varying iron oxide colourings depending on the tablet strength.
Foundayo contains less than 23 mg of sodium per tablet and is considered essentially sodium-free.
Like all medicines, Foundayo can cause side effects, although not everybody will experience them.
Very common side effects include:
- Feeling sick (nausea)
- Constipation
- Diarrhoea
- Vomiting
- Indigestion
- Stomach pain
These effects are often more noticeable when starting treatment or following a dose increase and may improve over time.
Other possible side effects include:
- Dizziness
- Headache
- Fast pulse
- Low blood pressure
- Bloating
- Heartburn or acid reflux
- Wind
- Gallstones
- Hair loss
- Tiredness
Seek urgent medical attention if you develop severe and persistent stomach pain, particularly if it spreads to your back, as this may be a sign of pancreatitis.
Speak to your clinician or pharmacist if you experience side effects that concern you.
Foundayo may not be suitable for everyone. Your treatment will be reviewed by a qualified clinician before it is prescribed.
Tell your clinician before taking Foundayo if you:
- Have previously had pancreatitis
- Have severe digestive problems or gastroparesis
- Have gallbladder problems
- Have diabetic retinopathy or other significant eye problems
- Have severe heart failure
- Take insulin or a sulfonylurea
- Take medicines for high blood pressure
- Are due to have surgery or an anaesthetic
Pregnancy: Foundayo should not be used during pregnancy. If you are planning a pregnancy, speak to your clinician. Treatment should be stopped at least three weeks before attempting to become pregnant.
Breastfeeding: Foundayo should not be used while breastfeeding.
Oral contraception: Foundayo may reduce the effectiveness of oral hormonal contraceptives. Additional barrier contraception or a non-oral method may be recommended for 30 days after starting treatment and for 30 days after each dose increase.
Always tell your clinician about any prescription medicines, over-the-counter medicines, supplements or herbal products you are taking.
Keep Foundayo out of the sight and reach of children.
- Keep the tablets in their original packaging.
- Protect the medicine from light.
- Do not use after the expiry date printed on the packaging.
Do not dispose of unused medicines in household waste or wastewater. Ask your pharmacist how to safely dispose of medicines you no longer require.
What is Foundayo?
Foundayo is a prescription weight management tablet containing orforglipron. It belongs to a group of medicines known as GLP-1 receptor agonists.
Is Foundayo a tablet?
Yes. Foundayo is taken orally once a day and does not require an injection.
Do I need to take Foundayo before food?
No. Foundayo can be taken at any time of day, with or without food.
How often do I take Foundayo?
Foundayo is taken once daily. Your clinician will prescribe the appropriate strength and advise you when your dose should be increased.
Who can take Foundayo for weight management?
Foundayo may be prescribed to adults with a BMI of 30 kg/m² or above, or adults with a BMI of at least 27 kg/m² and a qualifying weight-related health condition. Your suitability must be assessed by a clinician.
Can I take Foundayo while pregnant?
No. Foundayo should not be used during pregnancy.
Can I take Foundayo while breastfeeding?
No. Foundayo should not be used while breastfeeding.
What happens if I miss a dose?
Take the missed dose when you remember, but do not take more than one tablet in the same day.
Does Foundayo need to be refrigerated?
No. Keep the tablets in their original packaging and protect them from light.
Do I need a prescription?
Yes. Foundayo is a prescription-only medicine. At Livewell Dispensary, your consultation will be reviewed by a qualified UK prescriber before treatment can be supplied.
